Liisa Toose, MSc
Research Associate

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Liisa Toose completed her MSc at the Canadian Environmental Modelling Centre at Trent University in 2005 with Don Mackay. Her primary research experience includes the development and testing of mass balance models and chemical assessment systems such as:

  • risk assessment (e.g., RAIDAR);
  • bioaccumulation assessment (e.g., The BAT);
  • time-dependent, integrated field-scale fate and food web models (e.g., AGRO);
  • spatially-resolved models;
  • long-range transport of organic chemicals to arctic regions

She continues to be a part of the ARC model team working to improve model simulation capacity for ionic organic chemicals, bioaccumulation in plants, and waste water treatment plants.

EXPERIENCE
Research Associate | Toronto, ON (Remote)
Arnot Research and Consulting, Inc2012-Present
  • Compilation and curation of data reported in literature. Assessment of reported study field and laboratory practices.
  • Development, coding and application of Excel-based and online tools and models for the assessment of contaminant fate, exposure and bioaccumulation.
  • Various contracts developing and applying fate and bioaccumulation models to aid in regulatory assessment of chemicals in Canada, US and Europe
  • Presentation of research and results at conferences
  • Preparation of manuscripts for publication with co-authors


Research Associate
DMER, Ltd.2004-2012
Research Scientist, Graduate Student | Peterborough, ON
Canadian Environmental Modelling Centre2001-2009



Journal Publications

Arnot JA, Toose L, Armitage JM, Sangion A, Looky A, Brown TN, Li L, Becker RA. 2022. Developing an internal threshold of toxicological concern (iTTC). J Expo Sci Environ Epidemiol https://doi.org/10.1038/s41370-022-00494-x

Berthiaume A, Arnot JA, Toose L. 2022. Risk-based prioritization of organic substances in the Canadian National Pollutant Release Inventory using an evaluative regional-scale multimedia mass balance model. Integr Environ Assess Manag. https://doi.org/10.1002/ieam.4601

Arnot JA, Toose L, Armitage JM, Embry ME, Sangion A, Hughes L. 2022. A weight of evidence approach for bioaccumulation assessment. Integr Environ Assess Manag. https://doi.org/10.1002/ieam.4583

Li L, Sangion A, Wania F, Armitage JM, Toose L, Hughes L, Arnot JA. 2021. Development and evaluation of a holistic and mechanistic modeling framework for chemical emissions, fate, exposure, and risk. Environmental Health Perspectives 129:12 https://doi.org/10.1289/EHP9372

Armitage JM, Toose L, Camenzuli L, Redman AD, Parkerton TF, Saunders D, Wheeler J, Martin A, Vaiopoulou E, Arnot JA. 2021. A critical review and weight of evidence approach for assessing the bioaccumulation of phenanthrene in aquatic environments. Integr Environ Assess Manag, 17: 911-925. https://doi.org/10.1002/ieam.4401

Li L, Westgate JN, Hughes L, Zhang X, Givehchi B, Toose L, Armitage JM, Wania F, Egeghy P, Arnot JA. 2018. A model for risk-based screening and prioritization of near-field human exposure to chemicals. Environ Sci Technol 52(24): 14235-14244 http://dx.doi.org/10.1021/acs.est.8b04059

Toose L., Warren C, Mackay D, Parkerton T, Letinski D, Manning R, Connelly M, Rohde A, Fritz B, Hoffmann WC. 2015. Assessing the fate of an aromatic hydrocarbon fluid in agricultural spray applications using the three-stage ADVOCATE model framework. Journal of Agricultural and Food Chemistry 63(31), 6866-6875 http://dx.doi.org/10.1021/acs.jafc.5b01076

Gouin T, Armitage JM, Cousins I, Muir D, Ng C, Toose L, Tao S. 2013. Influence of global climate change on chemical fate and bioaccumulation: The role of multimedia models. Environmental toxicology and chemistry. 32. http://dx.doi.org/10.1002/etc.2044

Arnot JA, Armitage JM, McCarty LS, Wania F, Cousins I, Toose-Reid L. 2011. Toward a consistent evaluative framework for POP risk characterization. Environ Sci Technol 45(1): 97-103 Special Issue on Environmental Policy: Past, Present and Future – Invited https://doi.org/10.1021/es102551d

Toose L, Mackay D. 2004. Adaptation of fugacity models to treat speciating chemicals. Environ. Sci. Technol. 38: 4619-4626. https://doi.org/10.1021/es049957i

Toose L, Woodfine DG, MacLeod M, Mackay D, Gouin J. 2004. BETR-World: A geographically explicit model of chemical fate: Application to transport of a-HCH to the Arctic. Environ. Poll. 128: 223-240. https://doi.org/10.1016/j.envpol.2003.08.037

As Liisa Reid:

Webster E, Ellis DA, Reid LK. 2010. Modeling the environmental fate of perfluorooctanoic acid and perfluorooctanoate: An investigation of the role of individual species partitioning. Environ. Toxicol. Chem. 29(7): 1466 – 1475. https://doi.org/10.1002/etc.181

Mackay D, Reid LK. 2008. Local and distant residence times of contaminants in multi-compartment models. Part I: A review of the theoretical basis. Environ. Poll. 156: 1196-1203. https://doi.org/10.1016/j.envpol.2008.04.012

Reid LK, Mackay D. 2008. Local and distant residence times of contaminants in multi-compartment models. Part II: Application to assessing environmental mobility and long-range atmospheric transport. Environ. Poll. 156: 1182-1189. https://doi.org/10.1016/j.envpol.2008.04.011

McMurdo C.J, Ellis DA, Webster E, Butler J, Christensen RD, Reid LK. 2008. Aerosol enrichment of the surfactant PFO and mediation of the water - air transport of gaseous PFOA. Environ. Sci. Technol. 42 (11), 3969–3974. https://doi.org/10.1021/es7032026

Ethier A, Mackay D, Toose-Reid L, Lean D, O’Discoll N, Scheuhammer A. 2008. The Development and Application of a Mass Balance Model for Total Mercury in a Remote Lake using Multi-species Multiplier Method. Appl. Geochem. 23: 467-481. http://dx.doi.org/10.1016/j.apgeochem.2007.12.015

Technical Reports and Non-Refereed Publications

Toose L, Sangion A, Armitage, JM, Li, L, Arnot, JA. 2022. Case study and workshop for guiding the selection of appropriate exposure models for risk assessment using the EAS-E Suite platform. Final Report prepared for Heath Canada, New Substances Assessment and Control Bureau.

Arnot JA, Brown T, Toose L, Sangion A, Armitage JM. 2021. Modernize Health Canada’s Consumer and Industrial/Aquaculture release models and incorporate them into the EAS-E Suite platform. Prepared for Health Canada. Healthy Environments and Consumer Safety Branch. New Substances Assessment and Control Bureau.

Toose L, Armitage JM, Li L, Arnot JA. 2021. Analysis of far-field dietary exposures with food web considerations in human health assessment. Final Report prepared for Health Canada. Healthy Environments and Consumer Safety Branch. Safe Environments Directorate. Existing Substances Risk Assessment Bureau.

Arnot J., Toose L. 2019. Generation of a risk-ranking tool and ancillary input data for organic substances on the NPRI. Final Report prepared for Environment and Climate Change Canada.

Toose L, Armitage JM, Arnot JA. 2019. Phenanthrene Bioaccumulation Assessment using the Bioaccumulation Assessment Tool (BAT). Prepared for CONCAWE Ecology Group.

Arnot J, Toose L, Armitage J. 2018. Generation of physical-chemical property data and the application of models for estimating fate and transport and exposure and risk potential for organic substances on the Canadian DSL. Technical Report prepared for Environment and Climate Change Canada.

Arnot JA, McCarty LS, Armitage J, Toose-Reid L, Wania F, Cousins I. 2009. An evaluation of hexabromocyclododecane (HBCD) for persistent organic pollutant (POP) properties and the potential for adverse effects in the environment. Technical Report for European Brominated Flame Retardant Industry Panel (EBFRIP).

Toose L, Arnot J (in prep) Pilot project to parameterize and apply the RAIDAR model to assess chemical contaminants in the Great Lakes.

EDUCATION
M.Sc. Watershed Ecosystems Program
Trent University2005

Thesis: A Spatially-Explicit Global Mass Balance Model of Chemical Fate


Hons.B.Sc. Geography and Environmental Science
Trent University1994-2001



MODEL DEVELOPMENT AND CODING

EAS-E Suite Ver.l.9 – 0.95 RAIDAR, Point Source, Dilution, BET and F-PEST models (web app in R Shiny) www.eas-e-suite.com

BAT Ver.1.0 - 2.03 (Excel VBA) www.arnotresearch.com/BAT/

RAIDAR Ver.2.00 - 3.00 (Excel VBA) www.arnotresearch.com/RAIDAR/